Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 21 findings · 3 reviews

No studies found 4 · 19%GRADE not reported 0 · 0%Very low 3 · 14.3%Low 6 · 28.6%Moderate 8 · 38.1%High 0 · 0%

Iridotomy vs no iridotomy

Need for additional surgery: proportion of participants who received additional surgery to control IOP at 1 year · people with primary angle‐closure suspect

Iridotomy showed no clear difference in need for additional surgery: proportion of participants who received… compared with no iridotomy (low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants with IOP control (higher number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

Phacoemulsification may leads to higher proportion of participants with IOP control (higher number of events… compared with laser peripheral iridotomy (low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants requiring further IOP‐lowering interventions (additional surgery, medications, or both) (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants requiring further IOP‐lowering… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants with 1 or more recurrent APAC episodes in the same eye (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants with 1 or more recurrent APAC episodes in… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Progression of visual field loss (worsening of one or more stages, accordingto the Glaucoma Staging System‐2) (at 12 months) · participants with primary angle‐closure glaucoma

Phacoemulsification probably leads to lower progression of visual field loss (worsening of one or more stages,… compared with laser peripheral iridotomy (moderate certainty).

1 finding from 1 review