Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

154 questions · 161 findings · 14 reviews · Neuromuscular

No studies found 47 · 29.2%GRADE not reported 7 · 4.3%Very low 52 · 32.3%Low 33 · 20.5%Moderate 13 · 8.1%High 9 · 5.6%

Amantadine vs placebo

Reduction in fatigue · people with fatigue in Guillain‐Barré syndrome

Amantadine showed no clear difference in reduction in fatigue of at least 1‐point on the Fatigue Severity… compared with placebo (low certainty).

1 finding from 1 review

Amantadine vs placebo

Health related quality of life after 12 or more weeks or more after commencement of intervention (not reported) · people with fatigue in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review