Findings

What do systematic reviews say?

61 questions · 63 findings · 11 reviews · Breast Cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 30 · 47.6%Low 21 · 33.3%Moderate 8 · 12.7%High 4 · 6.3%

Summary of findings table ‐ Systemic therapy vs control

Change in pain from baseline to end of intervention · women with early breast cancer

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 183 participants
Very low

Summary of findings table ‐ Systemic therapy vs control

Change in grip strength · women with early breast cancer

Summary of findings table ‐ Systemic therapy showed no clear difference in change in grip strength from baseline to end of intervention compared with control (low certainty).

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
RR 1.08 [0.37, 3.17]
1 study · 137 participants
Low

Summary of findings table ‐ Systemic therapy vs control

Change in pain from baseline to end of intervention · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1099 participants
Very low

Summary of findings table ‐ Systemic therapy vs control

Change in stiffness from baseline to end of intervention · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 295 participants
Very low

Exercise vs usual care

Adverse effects secondary to the intervention · women with aromatase inhibitor‐induced musculoskeletal symptoms (AIMSS)

1 finding from 1 review

Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 331 participants
Low

Physical activity vs control

HRQOL (post‐intervention) · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 1996 participants
Low

Physical activity vs control

Physical function · women with breast cancer after adjuvant therapy

2 findings from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1433 participants
Moderate
Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
25 studies · 2129 participants
Moderate

Physical activity vs control

Anxiety change from baseline to end of intervention · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 235 participants
Low

Physical activity vs control

Depression change from baseline to end of intervention · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 816 participants
Very low

Physical activity vs control

Fatigue · women with breast cancer after adjuvant therapy

2 findings from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1289 participants
Low
Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
26 studies · 2020 participants
Moderate

Physical activity vs control

Cardiorespiratory fitness change from baseline to end of intervention · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 863 participants
Very low

Physical activity vs control

Emotional function/mental health at end of intervention · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
26 studies · 2102 participants
Moderate

Physical activity vs control

Anxiety · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 326 participants
Very low

Physical activity vs control

Depression at end of intervention · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 657 participants
Low

Physical activity vs control

Cardiorespiratory fitness (CF) (mL/kg/min) · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
23 studies · 1265 participants
Moderate

Physical activity vs control

HRQoL change from baseline to end of intervention · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 1459 participants
Low

Physical activity vs control

Emotional function/mental health change from baseline to end of intervention · women with breast cancer after adjuvant therapy

1 finding from 1 review

Physical activity for women with breast cancer after adjuvant therapy 2018 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 1579 participants
Low

Intervention not reported

Anxiety at end of intervention · women with breast cancer

1 finding from 1 review

Online support groups for women with breast cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Low

Intervention not reported

Depression at end of intervention · women with breast cancer

1 finding from 1 review

Online support groups for women with breast cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 120 participants
Very low

Intervention not reported

Quality of life post intervention · women with breast cancer

1 finding from 1 review

Online support groups for women with breast cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 140 participants
Very low