Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

94 questions · 102 findings · 12 reviews · Vascular

No studies found 16 · 15.7%GRADE not reported 1 · 1%Very low 17 · 16.7%Low 32 · 31.4%Moderate 27 · 26.5%High 9 · 8.8%

Cilostazol vs pentoxifylline

Adverse event related to study medication ‐ headache (number of cases) · intermittent claudication

Cilostazol may leads to higher adverse event related to study medication ‐ headache (number of cases) compared with pentoxifylline (low certainty).

1 finding from 1 review

Cilostazol vs placebo

Arterial revascularisation · intermittent claudication

It is very uncertain whether cilostazol changes arterial revascularisation (number of cases) compared with placebo (very low certainty).

1 finding from 1 review

Cilostazol vs placebo

Amputation · intermittent claudication

It is very uncertain whether cilostazol changes amputation (number of cases) compared with placebo (very low certainty).

1 finding from 1 review

Cilostazol vs placebo

Adverse event related to study medication ‐ headache (number of cases) · intermittent claudication

Cilostazol probably leads to higher adverse event related to study medication ‐ headache (number of cases) compared with placebo (moderate certainty).

1 finding from 1 review

Cilostazol vs placebo

Cardiovascular events · intermittent claudication

Cilostazol showed no clear difference in cardiovascular event (number of cases) compared with placebo (low certainty).

1 finding from 1 review