Findings

What do systematic reviews say?

157 questions · 162 findings · 17 reviews · Skin · Headline outcomes only

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No studies found 49 · 30.2%GRADE not reported 5 · 3.1%Very low 23 · 14.2%Low 41 · 25.3%Moderate 34 · 21%High 10 · 6.2%

Minoxidil 2% vs minoxidil 5%

Change in quality of life · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 209 participants
Low

Minoxidil 2% vs minoxidil 5%

Adverse events · women with FPHL

Minoxidil 2% showed no clear difference in adverse events compared with minoxidil 5% (low certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 1.02 [0.91, 1.2]
4 studies · 1006 participants
Low

Minoxidil 2% vs minoxidil 5%

Proportion of participants with investigator‐rated clinically significant hair regrowth · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 586 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Change from baseline to study conclusion in total hair count · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 631 participants
Low

Minoxidil 2% vs minoxidil 5%

Degree of hair shedding from baseline to the end of the study · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Minoxidil 2% vs minoxidil 5%

Cosmetic appearance of the hair or participant satisfaction · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Change in quality (or pattern) of hair regrowth (e.g. thickness) · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Proportion of participants with self‐rated clinically significant hair regrowth · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Low

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

Proportion of participants with adverse event · Participants with rosacea

Minocycline 45 mg showed no clear difference in proportion of participants with adverse event compared with minocycline 45 mg + azelaic acid gel (low certainty).

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
RR 0.69 [0.39, 1.22]
1 study · 60 participants
Low

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

Physician‐assessed improvement in rosacea severity · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

Assessment of erythema or telangiectasia · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

Lesion count · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

Time needed until improvement · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

Duration of remission ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NB‐UVB plus retinoid vs PUVA plus retinoid

Participant‐rated global improvement · People with chronic plaque or guttate psoriasis

1 finding from 1 review

Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

NB‐UVB plus retinoid vs PUVA plus retinoid

Percentage of participants reaching PASI 75 · People with chronic plaque or guttate psoriasis

NB‐UVB plus retinoid showed no clear difference in percentage of participants reaching PASI 75 compared with PUVA plus retinoid (low certainty).

1 finding from 1 review

Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
RR 0.89 [0.59, 1.35]
1 study · 60 participants
Low

NB‐UVB plus retinoid vs PUVA plus retinoid

Withdrawals due to adverse events · People with chronic plaque or guttate psoriasis

1 finding from 1 review

Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

NB‐UVB plus retinoid vs PUVA plus retinoid

Clearance rate · People with chronic plaque or guttate psoriasis

NB‐UVB plus retinoid showed no clear difference in clearance rate compared with PUVA plus retinoid (low certainty).

1 finding from 1 review

Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
RR 0.93 [0.79, 1.1]
2 studies · 90 participants
Low