Question · asked by 1 review

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel: Proportion of participants with adverse event

Population
Participants with rosacea
Intervention
Minocycline 45 mg
Comparison
minocycline 45 mg + azelaic acid gel
Outcome
Proportion of participants with adverse event

Minocycline 45 mg showed no clear difference in proportion of participants with adverse event compared with minocycline 45 mg + azelaic acid gel (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel
Proportion of participants with adverse event · Participants with rosacea
Minocycline 45 mg showed no clear difference in proportion of participants with adverse event compared with minocycline 45 mg + azelaic acid gel (low certainty).
Interventions for rosacea (2015) · Cochrane Headline outcomes only
RR 0.69 [0.39, 1.22]1 study · 60 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for rosacea
2015 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.