Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

20 questions · 21 findings · 6 reviews

No studies found 4 · 19%GRADE not reported 2 · 9.5%Very low 8 · 38.1%Low 7 · 33.3%Moderate 0 · 0%High 0 · 0%

IM pethidine vs placebo

Additional analgesia required (epidural, pethidine and Entonox) · women in labour

IM pethidine may leads to lower additional analgesia required (epidural, pethidine and Entonox) compared with placebo (low certainty).

1 finding from 1 review

IM pethidine vs placebo

Maternal satisfaction with analgesia measured during labour (number of women satisfied or very satisfied after 30 minutes) · women in labour

It is very uncertain whether IM pethidine changes maternal satisfaction with analgesia measured during labour (number… compared with placebo (very low certainty).

1 finding from 1 review

IM pethidine vs placebo

Maternal pain score or pain measured in labour (described as good or fair after 1 hour) · women in labour

IM pethidine may leads to higher maternal pain score or pain measured in labour (described as good or… compared with placebo (low certainty).

1 finding from 1 review

IM pethidine vs placebo

Maternal pain score or pain measured in labour (reduction in VAS of at least 40 mm after 30 minutes) · women in labour

IM pethidine may leads to higher maternal pain score or pain measured in labour (reduction in VAS of… compared with placebo (low certainty).

1 finding from 1 review

Patient-controlled analgesia (PCA) pethidine vs Staff-controlled delivery of pethidine

Daily mean opiate intake per hour · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Patient-controlled analgesia (PCA) pethidine showed no clear difference in daily mean opiate intake per hour compared with staff-controlled delivery of pethidine; GRADE not reported.

1 finding from 1 review

Patient-controlled analgesia (PCA) pethidine vs Staff-controlled delivery of pethidine

Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Patient-controlled analgesia (PCA) pethidine showed no clear difference in average pain scores (0-100 VAS) compared with staff-controlled delivery of pethidine; GRADE not reported.

1 finding from 1 review

Paracervical vs intravenous diazepam/pethidine analgesia

Providers' satisfaction with the procedure · women with persistent or prolonged retention of placenta

It is very uncertain whether paracervical block changes providers' satisfaction with the procedure compared with intravenous diazepam/pethidine analgesia (very low certainty).

1 finding from 1 review

Paracervical vs intravenous diazepam/pethidine analgesia

Women's satisfaction with the procedure · women with persistent or prolonged retention of placenta

It is very uncertain whether paracervical block changes women's satisfaction with the procedure compared with intravenous diazepam/pethidine analgesia (very low certainty).

1 finding from 1 review

Tramadol vs pethidine

Additional analgesia required (escape analgesia) · children undergoing surgery

It is very uncertain whether tramadol changes number of patients requiring rescue analgesia (PACU) compared with pethidine (very low certainty).

1 finding from 1 review

Tramadol vs pethidine

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

Tramadol showed no clear difference in number of patients with moderate to severe pain (PACU) compared with pethidine (low certainty).

1 finding from 1 review

Tramadol vs pethidine

Number of patients with PONV (PACU) · children undergoing surgery

Tramadol showed no clear difference in number of patients with PONV (PACU) compared with pethidine (low certainty).

1 finding from 1 review

Nalbuphine vs pethidine

Number of patients with the need for rescue analgesia (12 hours postoperatively) · children undergoing surgery

Nalbuphine showed no clear difference in number of patients with the need for rescue analgesia (2 hours… compared with pethidine (low certainty).

2 findings from 1 review