Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

80 questions · 80 findings · 11 reviews · Gynaecology and Fertility

No studies found 8 · 10%GRADE not reported 1 · 1.3%Very low 25 · 31.3%Low 35 · 43.8%Moderate 11 · 13.8%High 0 · 0%

Embryo culture supernatant injection vs no intervention

Live birth or ongoing pregnancy · Subfertile women undergoing assisted reproduction

It is very uncertain whether embryo culture supernatant injection changes live birth/ongoing pregnancy compared with no intervention (very low certainty).

1 finding from 1 review

Human chorionic gonadotropin (hCG) injection vs no treatment

Clinical pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes clinical pregnancy rate compared with no treatment (very low certainty).

1 finding from 1 review

Human chorionic gonadotropin (hCG) injection vs no treatment

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes multiple pregnancy rate compared with no treatment (very low certainty).

1 finding from 1 review

Intrauterine infusion of autologous platelet‐rich plasma vs no intervention

Live birth or ongoing pregnancy · women undergoing assisted reproduction

It is very uncertain whether intrauterine injection of autologous platelet‐rich plasma changes live birth (or ongoing pregnancy) compared with no intervention (very low certainty).

1 finding from 1 review

Intrauterine infusion of autologous platelet‐rich plasma vs no intervention

Adverse events: ectopic pregnancy · women undergoing assisted reproduction

It is very uncertain whether intrauterine injection of autologous platelet‐rich plasma changes adverse events: ectopic pregnancy compared with no intervention (very low certainty).

1 finding from 1 review

Intrauterine infusion/injection of autologous platelet‐rich plasma vs placebo or no intervention

Adverse events: preterm delivery · women undergoing assisted reproduction

Intrauterine infusion/injection of autologous platelet‐rich plasma may leads to higher adverse events: preterm delivery compared with no intervention or placebo (low certainty).

1 finding from 1 review

Intrauterine infusion/injection of autologous platelet‐rich plasma vs placebo or no intervention

Live birth or ongoing pregnancy · women undergoing assisted reproduction

It is very uncertain whether intrauterine infusion/injection of autologous platelet‐rich plasma changes live birth (or ongoing pregnancy) compared with no intervention or placebo (very low certainty).

1 finding from 1 review

Intrauterine infusion/injection of autologous platelet‐rich plasma vs placebo or no intervention

Miscarriage · women undergoing assisted reproduction

It is very uncertain whether intrauterine infusion/injection of autologous platelet‐rich plasma changes miscarriage compared with no intervention or placebo (very low certainty).

1 finding from 1 review