What do systematic reviews say?

Foam vs sclerotherapy (any sclerosant)

• Treatment for telangiectasias and reticular veins 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 187 participants
  Low

Foam vs sclerotherapy (any sclerosant)

Foam showed no clear difference in adverse events ‐ hyperpigmentation ( compared with sclerotherapy (any sclerosant) (low certainty).

• Treatment for telangiectasias and reticular veins 2021 · Cochrane Headline outcomes only
  RR 2.12 [0.44, 10.23]
  2 studies · 187 participants
  Low

Foam vs sclerotherapy (any sclerosant)

Foam may leads to higher adverse events ‐ matting ( compared with sclerotherapy (any sclerosant) (low certainty).

• Treatment for telangiectasias and reticular veins 2021 · Cochrane Headline outcomes only
  RR 6.12 [1.04, 35.98]
  2 studies · 187 participants
  Low

Foam vs sclerotherapy (any sclerosant)

• Treatment for telangiectasias and reticular veins 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 147 participants
  Low

Foam vs sclerotherapy (any sclerosant)

The review found no eligible studies for this question.

• Treatment for telangiectasias and reticular veins 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Foam vs sclerotherapy (any sclerosant)

The review found no eligible studies for this question.

• Treatment for telangiectasias and reticular veins 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Foam vs sclerotherapy (any sclerosant)

The review found no eligible studies for this question.

• Treatment for telangiectasias and reticular veins 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Foam sclerotherapy vs foam sclerotherapy

The review found no eligible studies for this question.

• Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Foam sclerotherapy vs foam sclerotherapy

The review found no eligible studies for this question.

• Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Foam sclerotherapy vs foam sclerotherapy

Foam sclerotherapy showed no clear difference in recurrent varicose veins compared with foam sclerotherapy (low certainty).

• Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
  RR 0.91 [0.62, 1.32]
  1 study · 148 participants
  Low

Foam sclerotherapy vs foam sclerotherapy

It is very uncertain whether foam sclerotherapy changes cosmetic appearance (self‐described cosmetic improvement) compared with foam sclerotherapy (very low certainty).

• Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
  RR 1.11 [0.84, 1.47]
  1 study · 80 participants
  Very low

Foam sclerotherapy vs foam sclerotherapy

It is very uncertain whether foam sclerotherapy changes complications ‐ thromboembolic compared with foam sclerotherapy (very low certainty).

• Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
  RR 1.47 [0.41, 5.33]
  3 studies · 371 participants
  Very low

Foam sclerotherapy vs foam sclerotherapy

Foam sclerotherapy showed no clear difference in residual varicose veins compared with foam sclerotherapy (moderate certainty).

• Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
  RR 0.67 [0.43, 1.04]
  3 studies · 371 participants
  Moderate

Ultrasound‐guided foam sclerotherapy vs conventional surgery

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  GRADE not reported

Ultrasound‐guided foam sclerotherapy vs conventional surgery

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  GRADE not reported

Ultrasound‐guided foam sclerotherapy vs conventional surgery

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 33 participants
  GRADE not reported
• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  GRADE not reported

Ultrasound‐guided foam sclerotherapy vs conventional surgery

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  GRADE not reported

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Ultrasound‐guided foam sclerotherapy showed no clear difference in recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (low certainty).

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  OR 0.34 [0.06, 2.1]
  1 study · 33 participants
  Low

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Ultrasound‐guided foam sclerotherapy showed no clear difference in recurrence of reflux at 1 year compared with conventional surgery (low certainty).

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  OR 1.19 [0.29, 4.92]
  1 study · 31 participants
  Low

Foam sclerotherapy vs placebo

• Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 223 participants
  Very low