What do systematic reviews say?

Fibrin glue vs Bascom's procedure

The review found no eligible studies for this question.

• Fibrin glue for pilonidal sinus disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fibrin glue vs Bascom's procedure

The review found no eligible studies for this question.

• Fibrin glue for pilonidal sinus disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fibrin glue instillation under skin flaps vs no‐fibrin

Fibrin glue instillation under skin flaps showed no clear difference in incidence of postoperativeseromaRR compared with no‐fibrin (low certainty).

• Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
  RR 1.02 [0.9, 1.16]
  18 studies · 1252 participants
  Low

Fibrin glue instillation under skin flaps vs no‐fibrin

• Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 731 participants
  Low

Fibrin glue instillation under skin flaps vs no‐fibrin

• Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 888 participants
  Low

Fibrin glue instillation under skin flaps vs no‐fibrin

• Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 861 participants
  Low

Fibrin glue instillation under skin flaps vs no‐fibrin

Fibrin glue instillation under skin flaps showed no clear difference in surgical site infectionRR compared with no‐fibrin (low certainty).

• Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
  RR 1.05 [0.63, 1.77]
  13 studies · 1009 participants
  Low

Fibrin glue instillation under skin flaps vs no‐fibrin

Fibrin glue instillation under skin flaps showed no clear difference in postoperativecomplicationsRR compared with no‐fibrin (low certainty).

• Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
  RR 1.13 [0.63, 2.04]
  11 studies · 981 participants
  Low

Fibrin glue instillation under skin flaps vs no‐fibrin

• Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 364 participants
  Low

Fibrin glue vs Conventional fistulotomy / seton

Fibrin glue showed no clear difference in recurrence simple fistula compared with conventional fistulotomy / seton (moderate certainty).

• Surgical intervention for anorectal fistula 2010 · Cochrane Headline outcomes only
  OR 15 [0.6, 376.7]
  1 study · 13 participants
  Moderate

Fibrin glue vs Conventional fistulotomy / seton

• Surgical intervention for anorectal fistula 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  High

Limberg flap plus fibrin glue vs off‐midline closure (Limberg flap)

• Fibrin glue for pilonidal sinus disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 132 participants
  Very low

Limberg flap plus fibrin glue vs off‐midline closure (Limberg flap)

It is very uncertain whether limberg flap plus fibrin glue changes adverse event (seroma) compared with limberg flap (very low certainty).

• Fibrin glue for pilonidal sinus disease 2017 · Cochrane Headline outcomes only
  RR 0.27 [0.05, 1.63]
  2 studies · 164 participants
  Very low

Karydakis flap plus fibrin glue vs Karydakis flap and drain

The review found no eligible studies for this question.

• Fibrin glue for pilonidal sinus disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Karydakis flap plus fibrin glue vs Karydakis flap and drain

It is very uncertain whether karydakis flap plus fibrin glue changes adverse event (seroma) compared with karydakis flap and drain (very low certainty).

• Fibrin glue for pilonidal sinus disease 2017 · Cochrane Headline outcomes only
  RR 3 [0.67, 13.46]
  1 study · 50 participants
  Very low

Advancement flap vs Fibrin glue with Flap repair

Advancement flap leads to lower recurrence compared with fibrin glue with Flap repair (high certainty).

• Surgical intervention for anorectal fistula 2010 · Cochrane Headline outcomes only
  OR 0.29 [0.09, 0.92]
  1 study · 58 participants
  High

Advancement flap vs Fibrin glue with Flap repair

• Surgical intervention for anorectal fistula 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 58 participants
  High

Intervention not reported

The intervention may leads to lower recurrence of pterygium ( (low certainty).

• Fibrin glue versus sutures for conjunctival autografting in primary pterygium surgery 2016 · Cochrane Headline outcomes only
  RR 0.47 [0.27, 0.82]
  Studies not reported
  Low

Intervention not reported

The intervention may leads to higher occurrence of complication (low certainty).

• Fibrin glue versus sutures for conjunctival autografting in primary pterygium surgery 2016 · Cochrane Headline outcomes only
  RR 1.92 [1.22, 3.02]
  Studies not reported
  Low

Intervention not reported

• Fibrin glue versus sutures for conjunctival autografting in primary pterygium surgery 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low