Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

259 questions · 272 findings · 23 reviews

No studies found 68 · 25%GRADE not reported 10 · 3.7%Very low 79 · 29%Low 57 · 21%Moderate 42 · 15.4%High 16 · 5.9%

Femoral vs subclavian insertion: short‐term catheterization

Immediate mechanical complications ‐ Total mechanical complications · critically ill patients

Femoral showed no clear difference in immediate mechanical complications ‐ Total mechanical complications compared with subclavian insertion: short‐term catheterization (high certainty).

1 finding from 1 review

Femoral vs subclavian insertion: short‐term catheterization

Immediate mechanical complications ‐ Major mechanical complications · critically ill patients

Femoral showed no clear difference in immediate mechanical complications ‐ Major mechanical complications compared with subclavian insertion: short‐term catheterization (high certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related infectious complications ‐ Catheter colonization · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter colonization compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related blood stream infection · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter related… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related infectious complication ‐ Subgroup Analysis for the effect of BMI on catheter colonization ‐ Highest BMI tercile (>28.4) · critically ill patients who were expected to require support with renal replacement therapy

Femoral probably leads to higher catheter‐related infectious complication ‐ Subgroup Analysis for the… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related thrombotic complications ‐ Symptomatic deep venous thrombosis · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related thrombotic complications ‐ Symptomatic deep venous… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Catheter‐related thrombosis at any time during catheter stay · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in catheter‐related thrombotic complications ‐ Catheter related… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Immediate mechanical complications ‐ Total mechanical complications · critically ill patients who were expected to require support with renal replacement therapy

Femoral probably leads to lower immediate mechanical complications ‐ Total mechanical complications compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs internal jugular insertion: short‐term catheterization

Immediate mechanical complications ‐ Major mechanical complications · critically ill patients who were expected to require support with renal replacement therapy

Femoral showed no clear difference in immediate mechanical complications ‐ Major mechanical complications compared with internal jugular insertion: short‐term catheterization (moderate certainty).

1 finding from 1 review

Femoral vs subclavian insertion: short‐term catheterization

Catheter‐related infectious complications ‐ Catheter colonization · critically ill patients

Femoral leads to higher catheter‐related infectious complications ‐ Catheter colonization compared with subclavian insertion: short‐term catheterization (high certainty).

1 finding from 1 review

Femoral vs subclavian insertion: short‐term catheterization

Catheter‐related blood stream infection · critically ill patients

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter‐related… compared with subclavian insertion: short‐term catheterization (high certainty).

1 finding from 1 review

Neuromuscular electrical stimulation + other intervention (e.g. exercise) vs other intervention alone

Kujala patellofemoral disorders score Scale from: 0 to 100 (higher scores = better function) · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…
1 finding from 1 review

Surgical vs non‐surgical treatment

Kujala patellofemoral disorders score Scale from: 0 to 100 (higher scores = better function) · people with lateral patellar dislocation

It is very uncertain whether surgical changes knee and physical functiona Measured using the Kujala patellofemoral… compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Zinc vs placebo

BMD Z score (total hip/femoral neck) · children and adults with β‐thalassaemia major and low bone mass

Summary of findings – zinc probably leads to higher BMD Z score (total hip/femoral neck) compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

BMD Z score (total hip/femoral neck) · people with β‐thalassaemia and osteoporosis

It is very uncertain whether the intervention changes BMD Z score (total hip/femoral neck) (very low certainty).

1 finding from 1 review