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What do systematic reviews say?

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Evidence found and GRADE certainty

116 questions · 116 findings · 6 reviews · Musculoskeletal · Headline outcomes only

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No studies found 41 · 35.3%GRADE not reported 3 · 2.6%Very low 8 · 6.9%Low 41 · 35.3%Moderate 11 · 9.5%High 12 · 10.3%

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Participant‐reported global assessment‐ total · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… probably leads to higher participant‐reported global assessment‐ total compared with land‐based exercise therapy (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Adverse events · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… showed no clear difference in adverse events compared with land‐based exercise therapy (low certainty).

1 finding from 1 review

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs placebo adjunctive therapies

Adverse events · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… showed no clear difference in adverse events compared with placebo adjunctive therapies (low certainty).

1 finding from 1 review