Findings

What do systematic reviews say?

11 questions · 11 findings · 2 reviews

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No studies found 6 · 54.5%GRADE not reported 0 · 0%Very low 5 · 45.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Esomeprazole vs fluticasone

Clinical improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs fluticasone

Clinical improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 67 participants
Very low

Esomeprazole vs fluticasone

Histological improvement (dichotomous) · active EoE patients

It is very uncertain whether esomeprazole changes histological improvement at 8 weeks (dichotomous) compared with fluticasone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.62 [0.77, 3.41]
2 studies · 72 participants
Very low

Esomeprazole vs fluticasone

Histological improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 70 participants
Very low

Esomeprazole vs fluticasone

Endoscopic improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs fluticasone

Endoscopic improvement (continuous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs fluticasone

Withdrawals due to adverse events · active EoE patients

It is very uncertain whether esomeprazole changes withdrawals due to adverse events at 8 weeks compared with fluticasone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.95 [0.07, 13.38]
2 studies · 72 participants
Very low

Esomeprazole vs placebo

Adverse events ‐ not reported · GORD in infants

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs placebo

pH indices ‐ not measured · GORD in infants

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs placebo

Endoscopic metrics ‐ not measured · GORD in infants

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs placebo

Improvement in symptoms and signs in infants · GORD in infants

1 finding from 1 review

Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 52 participants
Very low