Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

74 questions · 75 findings · 5 reviews · Hepato-Biliary · Headline outcomes only

No studies found 14 · 18.7%GRADE not reported 1 · 1.3%Very low 42 · 56%Low 5 · 6.7%Moderate 13 · 17.3%High 0 · 0%

Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation

Proportion of participants with ≥ 1 serious adverse events at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Endoscopic sphincterotomy changes proportion of participants with ≥ 1 serious adverse events at 1 year compared with endoscopic papillary balloon dilation (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy

Proportion of participants without successful treatment at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Biliary endoscopic sphincterotomy changes proportion of participants without successful treatment at 1 year compared with dual endoscopic sphincterotomy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Endoscopic sphincterotomy vs sham

Proportion of participants without successful treatment at longest · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Endoscopic sphincterotomy changes proportion of participants without successful treatment at longest compared with sham treatment (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Endoscopic sphincterotomy vs sham

Proportion of participants with ≥ 1 serious adverse events at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Endoscopic sphincterotomy changes proportion of participants with ≥ 1 serious adverse events at 1 year compared with sham treatment (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Endoscopic sphincterotomy vs sham

Quality of life · adults with biliary sphincter of Oddi dysfunction
2 findings from 1 review

Portosystemic shunts vs endoscopic intervention with or without medical treatment

All‐cause mortality · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether portosystemic shunts changes all‐cause mortality compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Total shunt vs endoscopic intervention

Mortality due to rebleeding · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether total shunt changes mortality due to rebleeding compared with endoscopic intervention (very low certainty).

1 finding from 1 review

Total shunt vs endoscopic intervention

Acute hepatic encephalopathy · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether total shunt changes acute hepatic encephalopathy compared with endoscopic intervention (very low certainty).

1 finding from 1 review

Distal splenorenal shunt vs endoscopic intervention

All‐cause mortality · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether distal splenorenal shunt changes all‐cause mortality compared with endoscopic intervention (very low certainty).

1 finding from 1 review