Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews · Orthodontics

No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Remineralizing orthodontic adhesives vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Enamel remineralization / anti-demineralization extent · Human teeth with early enamel lesions surrounding orthodontic brackets

No meta-analysis was conducted; most included in vitro studies reported significant remineralization with remineralizing orthodontic adhesives versus controls.

1 finding from 1 review

Remineralizing orthodontic adhesives vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Ion release · Human teeth with early enamel lesions surrounding orthodontic brackets

No meta-analysis was conducted; most studies reported increased ion release over time, but few reported peak values.

1 finding from 1 review