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Evidence found and GRADE certainty

7 questions · 7 findings · 3 reviews · Skin

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No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 2 · 28.6%High 0 · 0%

Bexarotene + PUVA vs PUVA

Common adverse effects ‐ Photosensitivity (Time point of measurement: up to 16 weeks) · people with mycosis fungoides

Bexarotene + PUVA showed no clear difference in common adverse effects ‐ Photosensitivity (Time point of… compared with PUVA alone (low certainty).

1 finding from 1 review

Bexarotene + PUVA vs PUVA

Objective response rate · people with mycosis fungoides

Bexarotene + PUVA showed no clear difference in objective response rate (Time point of measurement: up to 16 weeks) compared with PUVA alone (low certainty).

1 finding from 1 review

Gentamicin sponge vs primary closure

Adverse effects ‐ complication rate at 1 week after surgery · participants with hidradenitis suppurativa

Gentamicin sponge showed no clear difference in adverse effects ‐ complication rate at 1 week after surgery compared with primary closure alone (moderate certainty).

1 finding from 1 review

Gentamicin sponge vs primary closure

Adverse effects ‐ complication rate at 3 months after surgery · participants with hidradenitis suppurativa

Gentamicin sponge showed no clear difference in adverse effects ‐ complication rate at 3 months after surgery compared with primary closure alone (moderate certainty).

1 finding from 1 review

Imiquimod 5% cream with tazarotene 0.1% gel vs Imiquimod 5% cream alone

Discontinuation of treatment due to side effects ( · participants with melanoma in situ, including lentigo maligna

Imiquimod 5% cream with tazarotene 0.1% gel showed no clear difference in secondary outcome: Discontinuation of treatment because of harms… compared with imiquimod 5% cream alone (low certainty).

1 finding from 1 review