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What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 41.7%Low 1 · 8.3%Moderate 2 · 16.7%High 4 · 33.3%

Drug‐eluting balloon angioplasty at 6 months vs uncoated balloon angioplasty at 6 months

Target lesion revascularization · patients with in‐stent restenosis of the femoropopliteal arteries

It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes target lesion revascularization (TLR) compared with uncoated balloon angioplasty at 6 months (very low certainty).

1 finding from 1 review

Drug‐eluting balloon angioplasty at 6 months vs uncoated balloon angioplasty at 6 months

Binary restenosis · patients with in‐stent restenosis of the femoropopliteal arteries

It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes binary restenosis compared with uncoated balloon angioplasty at 6 months (very low certainty).

1 finding from 1 review

Drug‐eluting balloon angioplasty at 6 months vs uncoated balloon angioplasty at 6 months

Death · patients with in‐stent restenosis of the femoropopliteal arteries

It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes death compared with uncoated balloon angioplasty at 6 months (very low certainty).

1 finding from 1 review

Drug‐eluting balloon angioplasty at 6 months vs uncoated balloon angioplasty at 6 months

Improvement ≥ 1 Rutherford category · patients with in‐stent restenosis of the femoropopliteal arteries

It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes improvement ≥ 1 Rutherford category compared with uncoated balloon angioplasty at 6 months (very low certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Amputation · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon showed no clear difference in amputation compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Primary vessel patency · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon leads to higher primary vessel patency compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Target lesion revascularization · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon may leads to lower target lesion revascularization compared with uncoated balloon angioplasty at 12 months (low certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Binary restenosis · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon probably leads to lower binary restenosis compared with uncoated balloon angioplasty at 12 months (moderate certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Death · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon showed no clear difference in death compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review