Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews

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No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 2 · 25%Low 5 · 62.5%Moderate 0 · 0%High 0 · 0%

Discontinuation by no treatment/placebo of antihypertensives vs continuation

All‐cause mortality · Older adults, 50 years and older

Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in all‐cause mortality compared with continuation (low certainty).

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
OR 2.08 [0.79, 5.46]
4 studies · 630 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Fatal or nonfatal myocardial infarction · Older adults, 50 years and older

It is very uncertain whether discontinuation by no treatment/placebo of antihypertensives changes myocardial infarction (fatal and nonfatal) compared with continuation (very low certainty).

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
OR 1.86 [0.19, 17.98]
2 studies · 447 participants
Very low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Hospital admissions · Older adults, 50 years and older

Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in hospitalisation compared with continuation (low certainty).

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
OR 0.83 [0.33, 2.1]
1 study · 385 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Stroke (fatal + nonfatal + TIA) · Older adults, 50 years and older

Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in stroke (fatal + nonfatal + TIA) compared with continuation (low certainty).

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
OR 1.44 [0.25, 8.35]
3 studies · 524 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Systolic blood pressure · Older adults, 50 years and older

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 767 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Diastolic blood pressure · Older adults, 50 years and older

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 768 participants
Low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Adverse drug reactions and adverse drug withdrawal reactions (adverse reactions) · Older adults, 50 years and older

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 245 participants
Very low

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Falls ‐ not reported · Older adults, 50 years and older

The review found no eligible studies for this question.

1 finding from 1 review

Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found