Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

45 questions · 45 findings · 3 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 26 · 57.8%GRADE not reported 0 · 0%Very low 3 · 6.7%Low 6 · 13.3%Moderate 10 · 22.2%High 0 · 0%

Digital technology vs usual care

Exacerbations (number of people experiencing ≥ 1 exacerbations) · adolescents and adults with cystic fibrosis

Digital technology showed no clear difference in number of pulmonary exacerbations: number of participants… compared with usual care (moderate certainty).

1 finding from 1 review

Digital technology vs usual care

New micro‐organisms: number of participants in whom new organisms are detected · adolescents and adults with cystic fibrosis

Digital technology probably leads to lower new micro‐organisms: number of participants in whom new organisms… compared with usual care (moderate certainty).

1 finding from 1 review

Digital technology (web‐based platform CFHealthHub) vs usual care

Adherence to the inhaled treatment: percentage adherence · adults (aged 16 years and over) with CF

Digital technology (web‐based platform CFHealthHub) probably leads to higher adherence to the inhaled treatment: percentage adherence compared with usual care (moderate certainty).

1 finding from 1 review

Digital technology (web‐based platform CFHealthHub) vs usual care

Treatment burden · adults (aged 16 years and over) with CF

Digital technology (web‐based platform CFHealthHub) probably leads to higher treatment burden: CFQ‐R treatment burden domain score (higher score… compared with usual care (moderate certainty).

1 finding from 1 review