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What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews

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No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 57.1%Moderate 1 · 14.3%High 0 · 0%

Diacerein vs placebo

Radiographic progression—minimum joint space width (decreased over 0.50 mm during the study period) · patients with osteoarthritis

Diacerein may leads to lower radiographic progression—minimum joint space width (decreased over… compared with placebo (low certainty).

1 finding from 1 review

Diacerein vs placebo

Quality of life Not measured · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Diacerein vs placebo

Diarrhoea · patients with osteoarthritis

Diacerein may leads to higher adverse event: diarrhoea compared with placebo (low certainty).

1 finding from 1 review

Diacerein vs placebo

Withdrawals due to adverse events · patients with osteoarthritis

Diacerein showed no clear difference in withdrawal due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Diacerein vs placebo

Total number of serious adverse events not measured · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review