D‐cycloserine showed no clear difference in total adverse events compared with placebo (low certainty).
D‐cycloserine showed no clear difference in non‐core symptoms of ASD compared with placebo (low certainty).
D‐cycloserine showed no clear difference in tolerability compared with placebo (low certainty).
DCS and cognitive and behavioural therapies showed no clear difference in treatment efficacy: treatment responders As assessed per study compared with placebo and cognitive and behavioural therapies (low certainty).
DCS and cognitive and behavioural therapies showed no clear difference in in remission As assessed per study compared with placebo and cognitive and behavioural therapies (low certainty).
It is very uncertain whether DCS and cognitive and behavioural therapies changes condition‐specific anxiety symptoms As assessed by Y‐BOCS3 (scale… compared with placebo and cognitive and behavioural therapies (very low certainty).
It is very uncertain whether DCS and cognitive and behavioural therapies changes co‐morbid symptoms of depression As assessed by CDI5 (scale from 0… compared with placebo and cognitive and behavioural therapies (very low certainty).
The review found no eligible studies for this question.
DCS and cognitive and behavioural therapies showed no clear difference in treatment acceptability: withdrawals from treatment compared with placebo and cognitive and behavioural therapies (moderate certainty).
DCS and cognitive and behavioural therapies showed no clear difference in in remission As assessed per study compared with placebo and cognitive and behavioural therapies (moderate certainty).
DCS and cognitive and behavioural therapies showed no clear difference in condition‐specific anxiety symptoms As assessed by LSAS5 (scale… compared with placebo and cognitive and behavioural therapies (moderate certainty).
DCS and cognitive and behavioural therapies showed no clear difference in co‐morbid symptoms of depression As assessed by BDI‐II7 (scale from:… compared with placebo and cognitive and behavioural therapies (moderate certainty).
DCS and cognitive and behavioural therapies showed no clear difference in co‐morbid anxiety symptoms As assessed by BAI9 (scale from: 0 to 63,… compared with placebo and cognitive and behavioural therapies (low certainty).
It is very uncertain whether DCS and cognitive and behavioural therapies changes quality of life Assessed by LIS (scale from: 0 to 48, better… compared with placebo and cognitive and behavioural therapies (very low certainty).
DCS and cognitive and behavioural therapies showed no clear difference in treatment efficacy: treatment responders As assessed per study compared with placebo and cognitive and behavioural therapies (low certainty).
It is very uncertain whether DCS and cognitive and behavioural therapies changes treatment acceptability: withdrawals from treatment compared with placebo and cognitive and behavioural therapies (very low certainty).