Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

175 questions · 177 findings · 31 reviews

No studies found 18 · 10.2%GRADE not reported 33 · 18.6%Very low 50 · 28.2%Low 57 · 32.2%Moderate 19 · 10.7%High 0 · 0%

Biological graft vs native tissue repair

Recurrent posterior vaginal wall prolapse (objective failure) (12‐25 months) · women with posterior vaginal wall prolapse

Biological graft showed no clear difference in recurrent posterior vaginal wall prolapse (objective failure) (16‐24… compared with native tissue repair (low certainty).

1 finding from 1 review

Transanal repair vs transvaginal repair

Recurrent posterior vaginal wall prolapse (objective failure) (12‐25 months) · women with posterior vaginal wall prolapse

Transanal repair probably leads to higher recurrent posterior vaginal wall prolapse (objective failure) (12‐25… compared with transvaginal repair (moderate certainty).

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs active control

Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

tDCS vs sham

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with chronic pain

It is very uncertain whether transcranial direct current stimulation (tDCS) changes pain intensity (0 to < 1 week postintervention) measured using… compared with sham (very low certainty).

1 finding from 1 review

Post‐treatment exercise vs no intervention

Number of subjects with recurrent LBP · patients with recurrences of low‐back pain

Post‐treatment exercise probably leads to lower number of subjects with recurrent LBP compared with no intervention (moderate certainty).

2 findings from 1 review

Summary of findings: ACT vs CQ

Post‐treatment prophylaxis As assessed by: Recurrent parasitaemia between day 28 and day 42/56/63 · Adults and children with uncomplicated P. vivax malaria

Summary of findings: ACT may leads to lower post‐treatment prophylaxis As assessed by: Recurrent parasitaemia… compared with CQ (low certainty).

1 finding from 1 review

Summary of findings: DHA‐P vs alternative ACTs

Post treatment prophylaxis As assessed by: Recurrent parasitaemia between day 28 and 42 · Adults and children with uncomplicated P. vivax malaria

Summary of findings: DHA‐P may leads to lower post‐treatment prophylaxis As assessed by: Recurrent parasitaemia… compared with alternative ACTs (low certainty).

1 finding from 1 review

Betamethasone (systemic corticosteroid) vs Placebo or no treatment

Outcome not reported · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

The review found no eligible studies for this question.

1 finding from 1 review