Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

123 questions · 124 findings · 10 reviews · Kidney and Transplant

No studies found 45 · 36.3%GRADE not reported 0 · 0%Very low 20 · 16.1%Low 47 · 37.9%Moderate 10 · 8.1%High 2 · 1.6%

Subgroup analyses: early vs standard initiation of kidney replacement therapy (KRT)

Kidney recovery functionby KRT: continuous KRT · AKI

Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).

1 finding from 1 review

Subgroup analyses: early vs standard initiation of kidney replacement therapy (KRT)

Kidney recovery functionby KRT: continuous and intermittent KRT · AKI

Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous and intermittent KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).

1 finding from 1 review

Intervention not reported

Registration intention: ICC adjusted (continuous) · increasing solid organ donor registration
1 finding from 1 review

Intensive vs less intensive continuous renal replacement therapy (CRRT)

Patients free of RRT after discontinuing CRRT · AKI

Intensive showed no clear difference in patients free of RRT after discontinuing CRRT compared with less intensive continuous renal replacement therapy (CRRT) (low certainty).

2 findings from 1 review

Intensive vs less intensive continuous renal replacement therapy (CRRT)

Mortality: patients with AKI related to cardiac or general surgery · patients with AKI who need CRRT

Intensive leads to lower mortality: patients with AKI related to cardiac or general surgery compared with less intensive continuous renal replacement therapy (CRRT) (high certainty).

1 finding from 1 review

Intensive vs less intensive continuous renal replacement therapy (CRRT)

Mortality: patients with AKI not related to surgery · patients with AKI who need CRRT

Intensive showed no clear difference in mortality: patients with AKI not related to surgery compared with less intensive continuous renal replacement therapy (CRRT) (low certainty).

1 finding from 1 review