Question · asked by 1 review

Intensive vs less intensive continuous renal replacement therapy (CRRT): Patients free of RRT after discontinuing CRRT

Intensive showed no clear difference in patients free of RRT after discontinuing CRRT compared with less intensive continuous renal replacement therapy (CRRT) (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Intensive vs less intensive continuous renal replacement therapy (CRRT)
Patients free of RRT after discontinuing CRRT · patients with AKI
Intensive showed no clear difference in patients free of RRT after discontinuing CRRT compared with less intensive continuous renal replacement therapy (CRRT) (low certainty).
Intensity of continuous renal replacement therapy for acute kidney injury (2016) · Cochrane Headline outcomes only
RR 1.12 [0.91, 1.37]5 studies · 2402 participantsLow
Intensive vs less intensive continuous renal replacement therapy (CRRT)
Patients free of RRT after discontinuing CRRT · patients with AKI
Intensive showed no clear difference in patients free of RRT after discontinuing CRRT compared with less intensive continuous renal replacement therapy (CRRT) (moderate certainty).
Intensity of continuous renal replacement therapy for acute kidney injury (2016) · Cochrane Headline outcomes only
RR 0.98 [0.94, 1.01]3 studies · 988 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Intensity of continuous renal replacement therapy for acute kidney injury
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.