Total mortality · people with primary hypertension
It is very uncertain whether combination therapy changes total mortality compared with monotherapy (very low certainty).
1 finding from 1 review
Cardiovascular mortality · people with primary hypertension
1 finding from 1 review
Cardiovascular events · people with primary hypertension
It is very uncertain whether combination therapy changes cardiovascular events compared with monotherapy (very low certainty).
1 finding from 1 review
Serious adverse events · people with primary hypertension
It is very uncertain whether combination therapy changes serious adverse events compared with monotherapy (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with primary hypertension
It is very uncertain whether combination therapy changes withdrawals due to adverse effects compared with monotherapy (very low certainty).
1 finding from 1 review
Radiotherapy compliance · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
Combination chemotherapy probably leads to lower radiotherapy compliance compared with single‐agent chemotherapy (moderate certainty).
1 finding from 1 review
Chemotherapy compliance · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
Combination chemotherapy leads to lower chemotherapy compliance compared with single‐agent chemotherapy (high certainty).
1 finding from 1 review
Urologic symptom scores · men with lower urinary tract symptoms secondary to benign prostatic obstruction
1 finding from 1 review
Surgical intervention · men with lower urinary tract symptoms secondary to benign prostatic obstruction
It is very uncertain whether combination therapy changes surgical intervention compared with alpha‐blockers (very low certainty).
1 finding from 1 review
Urologic symptom scores · men with lower urinary tract symptoms secondary to benign prostatic obstruction
1 finding from 1 review
QoL · men with lower urinary tract symptoms secondary to benign prostatic obstruction
1 finding from 1 review
Adverse events · men with lower urinary tract symptoms secondary to benign prostatic obstruction
Combination therapy showed no clear difference in adverse events compared with anticholinergics (moderate certainty).
1 finding from 1 review
AUR · men with lower urinary tract symptoms secondary to benign prostatic obstruction
Combination therapy showed no clear difference in AUR compared with anticholinergics (low certainty).
1 finding from 1 review
Surgical intervention – not reported · men with lower urinary tract symptoms secondary to benign prostatic obstruction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
QoL · men with lower urinary tract symptoms secondary to benign prostatic obstruction
1 finding from 1 review
Adverse events · men with lower urinary tract symptoms secondary to benign prostatic obstruction
Combination therapy probably leads to higher adverse events compared with placebo (moderate certainty).
1 finding from 1 review
AUR · men with lower urinary tract symptoms secondary to benign prostatic obstruction
It is very uncertain whether combination therapy changes AUR compared with placebo (very low certainty).
1 finding from 1 review
Surgical intervention – not reported · men with lower urinary tract symptoms secondary to benign prostatic obstruction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Urologic symptom scores · men with lower urinary tract symptoms secondary to benign prostatic obstruction
1 finding from 1 review
QoL · men with lower urinary tract symptoms secondary to benign prostatic obstruction
1 finding from 1 review