Clinical cure · participants with confirmed toenail onychomycosis
It is very uncertain whether combination terbinafine plus azole changes clinical cure compared with terbinafine monotherapy (very low certainty).
1 finding from 1 review
Mycological cure · participants with confirmed toenail onychomycosis
It is very uncertain whether combination terbinafine plus azole changes mycological cure compared with terbinafine monotherapy (very low certainty).
1 finding from 1 review
Adverse events · participants with confirmed toenail onychomycosis
Combination terbinafine plus azole showed no clear difference in adverse events compared with terbinafine monotherapy (low certainty).
1 finding from 1 review
Recurrence · participants with confirmed toenail onychomycosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · participants with confirmed toenail onychomycosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Total effectiveness rate (Analysis 1.1) Clinician's rating · atopic eczema
Combination of oral and topical CHM showed no clear difference in total effectiveness rate (Analysis 3.1) Clinician's rating compared with same oral CHM (low certainty).
1 finding from 1 review
Overall severity score (Analysis 1.3) Clinician's rating. Scale from 1 to 80 · atopic eczema
1 finding from 1 review
QoL · atopic eczema
1 finding from 1 review
Adverse events (Analysis 1.7) Participant's report · atopic eczema
Combination of oral and topical CHM showed no clear difference in adverse events (Analysis 3.7) Participant's report compared with same oral CHM (low certainty).
1 finding from 1 review
Itching VAS (Analysis 1.2) Participant's rating. Scale from 1 to 10 · atopic eczema
1 finding from 1 review
Skin lesion score (Analysis 3.4) Clinician's rating. Scale from 0 to 24 · atopic eczema
1 finding from 1 review
Change from baseline in disease severity according to participants ‐ not measured · people with eczema
The review found no eligible studies for this question.
1 finding from 1 review
Participant satisfaction · people with eczema
1 finding from 1 review
Number of participants reporting an adverse event · people with eczema
It is very uncertain whether topical active treatment in combination with moisturiser changes number of participants reporting an adverse event compared with topical active treatment alone (very low certainty).
1 finding from 1 review
Change from baseline in disease severity as assessed by the investigators · people with eczema
1 finding from 1 review
Number of participants who experienced a flare · people with eczema
Topical active treatment in combination with moisturiser may leads to lower number of participants who experienced a flare compared with topical active treatment alone (low certainty).
1 finding from 1 review
Change in use of topical active treatment ‐ not measured · people with eczema
The review found no eligible studies for this question.
1 finding from 1 review
Change from baseline in health‐related quality of life · people with eczema
1 finding from 1 review
Mycological cure · patients with tinea cruris and tinea corporis
Azoles showed no clear difference in mycological cure Negative KOH microscopy and culture. Treatment… compared with moderate‐potent corticosteroid/azole combinations (low certainty).
1 finding from 1 review
Clinical cure · patients with tinea cruris and tinea corporis
It is very uncertain whether azoles changes clinical cure (immediately at end of treatment) Resolution of… compared with moderate‐potent corticosteroid/azole combinations (very low certainty).
1 finding from 1 review