Findings

What do systematic reviews say?

337 questions · 337 findings · 4 reviews · Anaesthesia · Headline outcomes only

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No studies found 55 · 16.3%GRADE not reported 138 · 40.9%Very low 67 · 19.9%Low 51 · 15.1%Moderate 19 · 5.6%High 7 · 2.1%

Acupoint PC6 stimulation and antiemetic combination vs antiemetics

Vomiting · People at risk of postoperative nausea and vomiting

It is very uncertain whether acupoint PC6 stimulation and antiemetic combination changes vomiting compared with antiemetic (very low certainty).

1 finding from 1 review

Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
RR 0.56 [0.35, 0.91]
9 studies · 687 participants
Very low

Acupoint PC6 stimulation and antiemetic combination vs antiemetics

Rescue antiemetic · People at risk of postoperative nausea and vomiting

Acupoint PC6 stimulation and antiemetic combination may leads to lower rescue antiemetic compared with antiemetic (low certainty).

1 finding from 1 review

Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
RR 0.61 [0.44, 0.86]
5 studies · 419 participants
Low

Acupoint PC6 stimulation and antiemetic combination vs antiemetics

Adverse effects · People at risk of postoperative nausea and vomiting

1 finding from 1 review

Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 7 participants
GRADE not reported

Acupoint PC6 stimulation and antiemetic combination vs antiemetics

Nausea · People at risk of postoperative nausea and vomiting

It is very uncertain whether acupoint PC6 stimulation and antiemetic combination changes nausea compared with antiemetic (very low certainty).

1 finding from 1 review

Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
RR 0.79 [0.55, 1.13]
8 studies · 642 participants
Very low

Automated mandatory bolus vs basal infusion

Breakthrough pain · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus probably leads to lower breakthrough pain compared with basal infusion (moderate certainty).

1 finding from 1 review

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour 2023 · Cochrane Headline outcomes only
RR 0.71 [0.55, 0.91]
16 studies · 1528 participants
Moderate

Automated mandatory bolus vs basal infusion

Caesarean delivery during labour epidural analgesia · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus showed no clear difference in caesarean delivery during labour epidural analgesia compared with basal infusion (moderate certainty).

1 finding from 1 review

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour 2023 · Cochrane Headline outcomes only
RR 0.85 [0.69, 1.06]
16 studies · 1735 participants
Moderate

Automated mandatory bolus vs basal infusion

Instrumental delivery during labour epidural analgesia · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus showed no clear difference in instrumental delivery during labour epidural analgesia compared with basal infusion (moderate certainty).

1 finding from 1 review

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour 2023 · Cochrane Headline outcomes only
RR 0.85 [0.71, 1.01]
17 studies · 4550 participants
Moderate

Automated mandatory bolus vs basal infusion

Duration of labour analgesia in minutes · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

1 finding from 1 review

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour 2023 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 4544 participants
Moderate

Automated mandatory bolus vs basal infusion

Local anaesthetic consumption per hour (mg/hr)c during labour epidural analgesia · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

1 finding from 1 review

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour 2023 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 1642 participants
Moderate

Automated mandatory bolus vs basal infusion

Maternal satisfaction following fetal delivery · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

1 finding from 1 review

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour 2023 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 14 participants
GRADE not reported

Automated mandatory bolus vs basal infusion

APGAR score (APGAR score ) · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

1 finding from 1 review

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour 2023 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 14 participants
GRADE not reported

Intervention not reported

Total studies: 282 RCTs Total participants: 50,812 Number of treatments: 65 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
282 studies · 50812 participants
GRADE not reported

Intervention not reported

Droperidol (41 RCTs; 6156 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
41 studies · 6156 participants
Moderate

Intervention not reported

Perphenazine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

NK1 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 participants
GRADE not reported

Intervention not reported

Aprepitant (1 RCT; 120 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 120 participants
Low

Intervention not reported

Casopitant (no direct evidence, indirect evidence only) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Fosaprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Rolapitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Corticosteroids · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

The review found no eligible studies for this question.

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found