Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews

No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 83.3%Moderate 0 · 0%High 0 · 0%

Citicoline vs standard methods versus placebo

Disability or dependence in daily activities Patients with moderate or lower degree of disability or dependence (according to < 3 scores in the modified Rankin scale) lower scores indicate better outcome · people with acute ischemic stroke

Citicoline showed no clear difference in disability or dependence in daily activities Patients with moderate… compared with placebo or standard treatment (low certainty).

1 finding from 1 review

Citicoline vs standard methods versus placebo

Functional recoveryPatients with scores in the Barthel Index ≥ 95 points · people with acute ischemic stroke

Citicoline showed no clear difference in functional recoveryPatients with scores in the Barthel Index ≥ 95… compared with placebo or standard treatment (low certainty).

1 finding from 1 review

Citicoline vs standard methods versus placebo

Neurological functionPatients with minor impairment (according to ≤ 1 scores in the National Institutes of Health Stroke Scale) · people with acute ischemic stroke

Citicoline showed no clear difference in neurological functionPatients with minor impairment (according to ≤… compared with placebo or standard treatment (low certainty).

1 finding from 1 review