Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

34 questions · 35 findings · 8 reviews · Headline outcomes only

No studies found 10 · 28.6%GRADE not reported 5 · 14.3%Very low 12 · 34.3%Low 8 · 22.9%Moderate 0 · 0%High 0 · 0%

Ciclosporin ophthalmic emulsion 0.05% vs artificial tears

Proportion of participants with adverse event · Participants with ocular rosacea

Ciclosporin ophthalmic emulsion 0.05% showed no clear difference in proportion of participants with adverse event compared with artificial tears (low certainty).

1 finding from 1 review

Any systemic treatment vs placebo

Ciclosporin · people with chronic plaque psoriasis

It is very uncertain whether any systemic treatment changes ciclosporin compared with placebo (very low certainty).

2 findings from 1 review