Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
At 36-month follow-up, HCSC show higher odds of clinical and radiographic success than CaOH (OR 2.34, 95% CI 1.43 to 3.84; ungraded subgroup).
3 findings from 1 review
OR 2.34 [1.43, 3.84]
2 studies · 379 participants
GRADE not reported
OR 4.44 [1.63, 12.07]
3 studies · 174 participants
GRADE not reported
OR 2.68 [1.7, 4.22]
5 studies · 552 participants
Moderate
Overall success (composite of clinical and radiographic success) · Adults (>=18 y) with mature permanent teeth, carious exposure and normal/reversibly inflamed pulp
At 1 year, partial pulpotomy and direct pulp capping (both calcium hydroxide) gave similarly low success in reversibly inflamed pulps (34.5% vs 31.8%; ungraded, single trial).
2 findings from 1 review
Success rate (%) 34.5 vs 31.8
1 study · 51 participants
GRADE not reported
Success rate (%) 11.1 vs 5.9
1 study · 44 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
CEM and calcium hydroxide did not differ significantly in pulpotomy success (indirect comparison); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
Partial pulpotomy with tri-calcium silicate cements (MTA/Biodentine) has a much higher success rate than with calcium hydroxide in adults (86.8% vs 34.3%; ungraded).
2 findings from 1 review
Dentin bridge formation · Patients with carious pulp exposure in permanent teeth undergoing partial pulpotomy
Evidence on dentin bridge formation for calcium hydroxide versus MTA is weak and imprecise, with no material shown superior (4 RCTs, not pooled; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth
In immature teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 2.22, 95% CI 0.13-36.67; very low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing direct pulp capping
For direct pulp capping, MTA probably achieves higher clinical and radiographic success than calcium hydroxide (OR 3.10, 95% CI 1.66-5.79; moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth of mixed/unspecified root maturation
In mixed-maturation teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 1.11, 95% CI 0.17-7.11; very low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy
For pulpotomy, whether MTA improves success over calcium hydroxide is uncertain (OR 2.36, 95% CI 0.47-11.75; low certainty; CI includes no effect).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing DPC or pulpotomy
Biodentine appeared to perform better than calcium hydroxide for success, but the evidence was not pooled (2 RCTs; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in mature permanent teeth
In mature teeth, MTA probably achieves higher clinical and radiographic success than calcium hydroxide (OR 3.34, 95% CI 1.81-6.17; moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing DPC or pulpotomy
MTA achieved higher clinical and radiographic success than calcium hydroxide overall (OR 2.94, 95% CI 1.96-4.49; low certainty), but this unadjusted estimate pools clinically heterogeneous DPC and pulpotomy studies.
1 finding from 1 review
Continued root formation / root development · Patients with carious pulp exposure in permanent teeth (predominantly immature) undergoing DPC or pulpotomy
Evidence on continued root formation for calcium hydroxide versus MTA is weak and inconclusive (3 RCTs, not pooled; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy
MTA and CEM performed comparably for clinical and radiographic success (2 RCTs, not pooled; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
Partial pulpotomy with calcium hydroxide had a pooled success rate of 34.3%.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
Partial pulpotomy with MTA or Biodentine had a pooled success rate of 86.8%.
1 finding from 1 review
Postoperative pain (patient-reported) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
The effect of material choice (MTA vs CaOH) on postoperative pain is unclear: two small studies used different methods and reported contradictory results, so no meta-analysis was performed (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
Biodentine and calcium hydroxide did not differ significantly in clinical and radiographic success (OR 3.14, 95% CI 0.91 to 10.86; ungraded subgroup analysis).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
Mineral trioxide aggregate shows higher odds of clinical and radiographic success than calcium hydroxide (OR 3.05, 95% CI 1.70 to 5.45; ungraded subgroup analysis).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
In partial pulpotomy, MTA had significantly higher success than calcium hydroxide (OR 2.81; ungraded).
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