Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

93 questions · 101 findings · 2 reviews · Skin

No studies found 59 · 58.4%GRADE not reported 2 · 2%Very low 39 · 38.6%Low 0 · 0%Moderate 1 · 1%High 0 · 0%

1% pimecrolimus cream vs Placebo (vehicle cream)

Physician Global Assessment (weighted sums of ulceration, erythema, reticulation, mm2) · People with erosive oral lichen planus

1% pimecrolimus cream showed no clear difference in physician Global Assessment (weighted sums of ulceration, erythema,… compared with placebo (vehicle cream); GRADE not reported.

1 finding from 1 review

Zinc tape vs magnesium sulphate glycerin

Ulcer healing · ulceration caused by nerve damage in leprosy

It is very uncertain whether zinc tape changes primary outcome: healing of ulcers (number of ulcers healed after 1… compared with magnesium sulphate glycerin (very low certainty).

2 findings from 1 review

Topical ketanserin (2%) vs clioquinol cream (3%) or zinc paste

Ulcer healing · ulceration caused by nerve damage in leprosy

It is very uncertain whether topical ketanserin (2%) changes primary outcome: healing of ulcers (healing of ulcer at 3 months) compared with clioquinol cream (3%) or zinc paste (very low certainty).

1 finding from 1 review