Question · asked by 1 review

Topical ketanserin (2%) vs clioquinol cream (3%) or zinc paste: Primary outcome: adverse events (assessed at 3 months as minimum, moderate or severe)

Population
ulceration caused by nerve damage in leprosy
Intervention
Topical ketanserin (2%)
Comparison
clioquinol cream (3%) or zinc paste
Outcome
Primary outcome: adverse events (assessed at 3 months as minimum, moderate or severe)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Topical ketanserin (2%) vs clioquinol cream (3%) or zinc paste
Primary outcome: adverse events (assessed at 3 months as minimum, moderate or severe) · ulceration caused by nerve damage in leprosy
Interventions for ulceration and other skin changes caused by nerve damage in leprosy (2019) · Cochrane Headline outcomes only
no estimate extracted1 study · 66 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for ulceration and other skin changes caused by nerve damage in leprosy
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.