Findings

What do systematic reviews say?

9 questions · 9 findings · 1 reviews · Kidney and Transplant

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 55.6%Moderate 4 · 44.4%High 0 · 0%

Intervention not reported

Mortality · patients with acute kidney injury

The intervention showed no clear difference in mortality (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.76 [0.5, 1.15]
3 studies · 163 participants
Moderate

Intervention not reported

Serum bicarbonate (mmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 163 participants
Low

Intervention not reported

Serum creatinine (µmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 137 participants
Low

Intervention not reported

Serum lactate (mmol/L) · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 171 participants
Moderate

Intervention not reported

Serum base excess · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 145 participants
Low

Intervention not reported

Serum pH · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 171 participants
Low

Intervention not reported

pCO2 · patients with acute kidney injury

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 151 participants
Low

Intervention not reported

Hypotensive events · patients with acute kidney injury

The intervention probably leads to lower hypotensive events (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.44 [0.26, 0.75]
1 study · 20 participants
Moderate

Intervention not reported

Cardiovascular complications · patients with acute kidney injury

The intervention probably leads to lower cardiovascular complications (moderate certainty).

1 finding from 1 review

Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration 2015 · Cochrane Headline outcomes only
RR 0.39
1 study · 20 participants
Moderate