Cochrane · systematic review · CD006819
Bicarbonate‐ versus lactate‐buffered solutions for acute continuous haemodiafiltration or haemofiltration
Tian, JH, Ma, B, Yang, K, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 55.6%Moderate 4 · 44.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: patients with acute kidney injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality | RR 0.76 [0.5, 1.15] | 3 studies · 163 participants | Moderate |
Serum bicarbonate (mmol/L) | no estimate extracted | 3 studies · 163 participants | Low |
Serum creatinine (µmol/L) | no estimate extracted | 2 studies · 137 participants | Low |
Serum lactate (mmol/L) | no estimate extracted | 4 studies · 171 participants | Moderate |
Serum base excess | no estimate extracted | 3 studies · 145 participants | Low |
Serum pH | no estimate extracted | 4 studies · 171 participants | Low |
pCO2 | no estimate extracted | 3 studies · 151 participants | Low |
Hypotensive events | RR 0.44 [0.26, 0.75] | 1 study · 20 participants | Moderate |
Cardiovascular complications | RR 0.39 | 1 study · 20 participants | Moderate |