Improved or corrected strabismusa at 6 or 12 months · adults and children with strabismus
Botulinum toxin may leads to lower improved or corrected strabismusa at 6 or 12 months compared with surgery (low certainty).
1 finding from 1 review
Serious adverse events at 6 or 12 months · adults and children with strabismus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants requiring additional surgery(ies) at 6 or 12 months · adults and children with strabismus
It is very uncertain whether botulinum toxin changes proportion of participants requiring additional surgery(ies) at 6 or… compared with surgery (very low certainty).
1 finding from 1 review
Proportion of participants who achieved binocular single vision at 6 or 12 months · adults and children with strabismus
Botulinum toxin showed no clear difference in proportion of participants who achieved binocular single vision at 6… compared with surgery (low certainty).
1 finding from 1 review
Quality of life (validated questionnaire) · adults and children with strabismus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐serious adverse events at 6 or 12 months · adults and children with strabismus
1 finding from 1 review
Improvement in ocular motility (ocular alignment ≤ 10 prism dioptres). · people with sixth nerve palsy
Botulinum toxin showed no clear difference in improvement in ocular motility (ocular alignment ≤ 10 prism dioptres). compared with observation (low certainty).
1 finding from 1 review
Secondary outcome: achievement of binocular single vision · people with sixth nerve palsy
Botulinum toxin showed no clear difference in achievement of binocular single vision (fusion and stereopsis… compared with observation (low certainty).
1 finding from 1 review
Improvement in functional ability · people with sixth nerve palsy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · people with sixth nerve palsy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events. · people with sixth nerve palsy
1 finding from 1 review
Treatment success: improvement in the angle of strabismus at 6 months · children with infantile esotropia
It is very uncertain whether surgery changes treatment success: improvement in the angle of strabismus at 6 months compared with botulinum neurotoxin injections (very low certainty).
1 finding from 1 review
Presence and quality of binocularity at 6 months · children with infantile esotropia
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects (severe, minor) at 6 months · children with infantile esotropia
1 finding from 1 review