Cardiovascular mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin showed no clear difference in cardiovascular mortality compared with aspirin alone (moderate certainty).
1 finding from 1 review
All‐cause mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin showed no clear difference in all‐cause mortality compared with aspirin alone (low certainty).
1 finding from 1 review
Fatal or nonfatal myocardial infarction · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to lower fatal and non‐fatal myocardial infarction compared with aspirin alone (moderate certainty).
1 finding from 1 review
Fatal and non‐fatal ischaemic stroke · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to lower fatal and non‐fatal ischaemic stroke compared with aspirin alone (moderate certainty).
1 finding from 1 review
Adverse events · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
1 finding from 1 review
Major bleeding · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to higher major bleeding compared with aspirin alone (moderate certainty).
1 finding from 1 review
Minor bleeding · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to higher minor bleeding compared with aspirin alone (moderate certainty).
1 finding from 1 review
All‐cause mortality · patients with heart failure with sinus rhythm
Summary of findings: warfarin showed no clear difference in all‐cause mortality compared with aspirin (moderate certainty).
1 finding from 1 review
Non‐fatal cardiovascular events · patients with heart failure with sinus rhythm
Summary of findings: warfarin showed no clear difference in non‐fatal cardiovascular events (non‐fatal stroke, myocardial… compared with aspirin (moderate certainty).
1 finding from 1 review
Major bleeding · patients with heart failure with sinus rhythm
Summary of findings: warfarin probably leads to higher major bleeding events compared with aspirin (moderate certainty).
1 finding from 1 review