Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Emergency and Critical Care

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 57.1%Low 0 · 0%Moderate 3 · 42.9%High 0 · 0%

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Mortality (subgroup analysis on bias risk) · critically ill participants

The intervention showed no clear difference in mortality (subgroup analysis on bias risk) (moderate certainty).

1 finding from 1 review

Antithrombin III for critically ill patients 2016 · Cochrane Headline outcomes only
RR 0.95 [0.88, 1.03]
29 studies · 3882 participants
Moderate

Bleeding events · critically ill participants

The intervention probably leads to higher bleeding events (moderate certainty).

1 finding from 1 review

Antithrombin III for critically ill patients 2016 · Cochrane Headline outcomes only
RR 1.58 [1.35, 1.84]
11 studies · 3019 participants
Moderate

Incidence of respiratory failure not present at admission · critically ill participants

The intervention showed no clear difference in incidence of respiratory failure not present at admission (moderate certainty).

1 finding from 1 review

Antithrombin III for critically ill patients 2016 · Cochrane Headline outcomes only
RR 0.93 [0.76, 1.14]
6 studies · 2591 participants
Moderate

Duration of mechanical ventilation · critically ill participants

1 finding from 1 review

Antithrombin III for critically ill patients 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 190 participants
Very low

Length of stay in hospital · critically ill participants

1 finding from 1 review

Antithrombin III for critically ill patients 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 202 participants
Very low

Mean length of stay in ICU · critically ill participants

1 finding from 1 review

Antithrombin III for critically ill patients 2016 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 376 participants
Very low

Overall mortality among patients with severe sepsis & DIC · critically ill participants

It is very uncertain whether the intervention changes overall mortality among patients with severe sepsis & DIC (very low certainty).

1 finding from 1 review

Antithrombin III for critically ill patients 2016 · Cochrane Headline outcomes only
RR 0.95 [0.88, 1.03]
12 studies · 2858 participants
Very low