Findings

What do systematic reviews say?

6 questions · 6 findings · 2 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 1 · 16.7%Very low 1 · 16.7%Low 1 · 16.7%Moderate 1 · 16.7%High 2 · 33.3%

Antibiotic prophylaxis vs no treatment or placebo

Individual antimicrobial resistance · Women who had normal vaginal births

1 finding from 1 review

Routine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Single‐dose antibiotic vs short duration antibiotics

Pyelonephritis ‐ Same antimicrobial agent only4 · patients with asymptomatic bacteriuria during pregnancy

It is very uncertain whether single‐dose antibiotic changes pyelonephritis ‐ Same antimicrobial agent only4 compared with short‐course (four‐ to seven‐day) antibiotic (very low certainty).

1 finding from 1 review

Duration of treatment for asymptomatic bacteriuria during pregnancy 2015 · Cochrane Headline outcomes only
RR 3.09 [0.54, 17.55]
2 studies · 102 participants
Very low

Single‐dose antibiotic vs short duration antibiotics

Low birthweight ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic leads to higher low birthweight ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).

1 finding from 1 review

Duration of treatment for asymptomatic bacteriuria during pregnancy 2015 · Cochrane Headline outcomes only
RR 1.65 [1.06, 2.57]
1 study · 714 participants
High

Single‐dose antibiotic vs short duration antibiotics

Preterm delivery ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic showed no clear difference in preterm delivery ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (moderate certainty).

1 finding from 1 review

Duration of treatment for asymptomatic bacteriuria during pregnancy 2015 · Cochrane Headline outcomes only
RR 1.17 [0.77, 1.78]
3 studies · 804 participants
Moderate

Single‐dose antibiotic vs short duration antibiotics

Same antimicrobial agent ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic leads to higher same antimicrobial agent ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).

1 finding from 1 review

Duration of treatment for asymptomatic bacteriuria during pregnancy 2015 · Cochrane Headline outcomes only
RR 1.72 [1.27, 2.33]
2 studies · 803 participants
High

Single‐dose antibiotic vs short duration antibiotics

Different antimicrobial agents ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic showed no clear difference in different antimicrobial agents ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (low certainty).

1 finding from 1 review

Duration of treatment for asymptomatic bacteriuria during pregnancy 2015 · Cochrane Headline outcomes only
RR 1.36 [0.24, 7.75]
1 study · 84 participants
Low