Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Anaesthesia

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

CHRONIC: ACEi or ARB vs placebo

All‐cause mortality · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively

It is very uncertain whether ACEIs or ARBs changes all‐cause mortality compared with placebo (very low certainty).

1 finding from 1 review

Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes only
RR 1.61 [0.44, 5.85]
3 studies · 419 participants
Very low

CHRONIC: ACEi or ARB vs placebo

Risk of acute myocardial ischaemia · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively

It is very uncertain whether ACEIs or ARBs changes risk of acute myocardial ischaemia compared with placebo (very low certainty).

1 finding from 1 review

Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes only
RR 0.55 [0.14, 2.26]
2 studies · 345 participants
Very low

CHRONIC: ACEi or ARB vs placebo

Congestive heart failure · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively

1 finding from 1 review

Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 34 participants
Very low

CHRONIC: ACEi or ARB vs placebo

Hypotension · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively

It is very uncertain whether ACEIs or ARBs changes hypotension compared with placebo (very low certainty).

1 finding from 1 review

Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes only
RR 1.95 [0.86, 4.41]
1 study · 298 participants
Very low

CHRONIC: ACEi or ARB vs placebo

Rate of perioperative cerebrovascular complications · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively

It is very uncertain whether ACEIs or ARBs changes rate of perioperative cerebrovascular complications compared with placebo (very low certainty).

1 finding from 1 review

Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes only
RR 0.48 [0.18, 1.28]
3 studies · 459 participants
Very low

CHRONIC: ACEi or ARB vs placebo

Length of hospital stay · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively

1 finding from 1 review

Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 372 participants
Very low

CHRONIC: ACEi or ARB vs placebo

Treatment related adverse events · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively

1 finding from 1 review

Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 385 participants
Very low