Findings

What do systematic reviews say?

3 questions · 6 findings · 1 reviews · Heart

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 2 · 33.3%High 1 · 16.7%

Survival to hospital discharge · participants with bradyasystolic cardiac arrest in adults

Aminophylline showed no clear difference in survival to hospital discharge compared with placebo (moderate certainty).

2 findings from 1 review

Aminophylline for bradyasystolic cardiac arrest in adults 2015 · Cochrane Headline outcomes only
OR 0.58 [0.12, 2.74]
5 studies · 1254 participants
Moderate
Aminophylline for bradyasystolic cardiac arrest in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 37 participants
Low

Return of spontaneous circulation · participants with bradyasystolic cardiac arrest in adults

Aminophylline showed no clear difference in return of spontaneous circulation compared with placebo (high certainty).

2 findings from 1 review

Aminophylline for bradyasystolic cardiac arrest in adults 2015 · Cochrane Headline outcomes only
OR 1.15 [0.89, 1.49]
5 studies · 1254 participants
High
Aminophylline for bradyasystolic cardiac arrest in adults 2015 · Cochrane Headline outcomes only
OR 1.61 [0.38, 6.77]
2 studies · 37 participants
Low

Early administration of aminophylline: survival to hospital admission · participants with bradyasystolic cardiac arrest in adults

Aminophylline showed no clear difference in survival to admission compared with placebo (moderate certainty).

2 findings from 1 review

Aminophylline for bradyasystolic cardiac arrest in adults 2015 · Cochrane Headline outcomes only
OR 0.92 [0.61, 1.39]
4 studies · 1232 participants
Moderate
Aminophylline for bradyasystolic cardiac arrest in adults 2015 · Cochrane Headline outcomes only
OR 0.22 [0.02, 2.36]
2 studies · 37 participants
Low