Findings

What do systematic reviews say?

8 questions · 8 findings · 2 reviews · Neuromuscular

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No studies found 4 · 50%GRADE not reported 2 · 25%Very low 0 · 0%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Amantadine vs placebo

Activity limitations ‐ not measured · people with postpolio syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
GRADE not reported

Amantadine vs placebo

Reduction in fatigue · people with fatigue in Guillain‐Barré syndrome

Amantadine showed no clear difference in reduction in fatigue of at least 1‐point on the Fatigue Severity… compared with placebo (low certainty).

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
OR 0.56 [0.22, 1.35]
74 participants
Low

Amantadine vs placebo

Fatigue · people with fatigue in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Change in activity limitations · people with fatigue in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Participation · people with fatigue in Guillain‐Barré syndrome

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
74 participants
Low

Amantadine vs placebo

Health related quality of life after 12 or more weeks or more after commencement of intervention (not reported) · people with fatigue in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Serious adverse events · people with fatigue in Guillain‐Barré syndrome

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
80 participants
GRADE not reported