Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 5 · 100%High 0 · 0%

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Time‐to‐tolerance of a solid diet and documented bowel movements

Alvimopan probably leads to higher time‐to‐tolerance of a solid diet and documented bowel movements compared with placebo (moderate certainty).

1 finding from 1 review

Alvimopan for recovery of bowel function after radical cystectomy 2017 · Cochrane Headline outcomes only
HR 1.77 [1.41, 2.23]
1 study · 277 participants
Moderate

Time to hospital discharge

Alvimopan probably leads to higher time‐to‐hospital discharge compared with placebo (moderate certainty).

1 finding from 1 review

Alvimopan for recovery of bowel function after radical cystectomy 2017 · Cochrane Headline outcomes only
HR 1.67 [1.38, 2.01]
1 study · 277 participants
Moderate

Major adverse events

Alvimopan probably leads to lower major adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Alvimopan for recovery of bowel function after radical cystectomy 2017 · Cochrane Headline outcomes only
RR 0.28 [0.18, 0.44]
1 study · 277 participants
Moderate

Patient readmissions

Alvimopan showed no clear difference in readmission compared with placebo (moderate certainty).

1 finding from 1 review

Alvimopan for recovery of bowel function after radical cystectomy 2017 · Cochrane Headline outcomes only
RR 0.89 [0.59, 1.33]
1 study · 277 participants
Moderate

Cardiovascular events

Alvimopan showed no clear difference in any cardiovascular event compared with placebo (moderate certainty).

1 finding from 1 review

Alvimopan for recovery of bowel function after radical cystectomy 2017 · Cochrane Headline outcomes only
RR 0.54 [0.27, 1.05]
1 study · 277 participants
Moderate