Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

IMMEDIATE initiation of cART vs DEFERRED initiation of cART

Patient or population: HIV‐positive, treatment‐naive children aged 24 to 59 months (2 to 5 years old)Settings: Thailand and CambodiaIntervention: IMMEDIATE initiation of cARTComparison: DEFERRED initiation of cART · HIV‐positive, treatment‐naive children aged one to 12 years old

The review found no eligible studies for this question.

1 finding from 1 review

Engagement of community leaders vs usual care

Proportion of children who received DTP3 or Penta 3 by 1 year of age · children under 5 years of age

Engagement of community leaders probably leads to higher proportion of children who received DTP3 or Penta 3 by 1 year of age compared with routine care (moderate certainty).

1 finding from 1 review

Monetary incentives vs usual care

Proportion of children under 5 years of age fully immunised with all scheduled vaccines · children under 5 years of age

It is very uncertain whether monetary incentives changes proportion of children under 5 years of age fully immunised with all… compared with routine care (very low certainty).

1 finding from 1 review

Digital register vs usual care

Proportion of children who received all recommended vaccines by 2 years of age · children under 5 years of age

Digital register showed no clear difference in proportion of children who received all recommended vaccines by 2… compared with routine care (low certainty).

1 finding from 1 review

Phone call/SMS with/without combination with monetary incentives vs usual care

Proportion of children who received all recommended vaccines by 2 years of age (phone call/SMS only) · children under 5 years of age

Phone call/SMS with/without combination with monetary incentives showed no clear difference in proportion of children who received all recommended vaccines by 2… compared with routine care (low certainty).

1 finding from 1 review

Phone call/SMS with/without combination with monetary incentives vs usual care

Proportion of children who received all recommended vaccines by 2 years of age · children under 5 years of age

Phone call/SMS with/without combination with monetary incentives may leads to higher proportion of children who received all recommended vaccines by 2… compared with routine care (low certainty).

1 finding from 1 review

Training of health providers vs usual care

Proportion of children who received all recommended vaccines by 2 years of age · children under 5 years of age

It is very uncertain whether training of health providers changes proportion of children who received all recommended vaccines by 2… compared with routine care (very low certainty).

1 finding from 1 review

Home visit vs usual care

Proportion of children who received all recommended vaccines by 2 years of age · children under 5 years of age

It is very uncertain whether home visit changes proportion of children who received all recommended vaccines by 2… compared with routine care (very low certainty).

1 finding from 1 review

Immunisation outreach vs usual care

Proportion of children who received all recommended vaccines by 25 years of age · children under 5 years of age

It is very uncertain whether immunisation outreach changes proportion of children who received all recommended vaccines by 25… compared with routine care (very low certainty).

1 finding from 1 review

Immunisation outreach vs usual care

Fully immunised children ( · children under 5 years of age

Immunisation outreach probably leads to higher proportion of children under 5 years of age fully immunised with all… compared with routine care (moderate certainty).

2 findings from 1 review