Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 6 reviews · Infectious Diseases · Headline outcomes only

No studies found 0 · 0%GRADE not reported 2 · 20%Very low 3 · 30%Low 2 · 20%Moderate 2 · 20%High 1 · 10%

MVA85A vs placebo

Active tuberculosis: started on tuberculosis treatment · HIV‐positive and ‐negative adults and children

MVA85A showed no clear difference in active tuberculosis: started on tuberculosis treatment compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Cure or completion of treatment for active TB · Recipients of TB control services

The intervention showed no clear difference in cure or completion of treatment for active TB (low certainty).

1 finding from 1 review

Intervention not reported

Treatment completion · adults and children with active tuberculosis

It is very uncertain whether the intervention changes treatment completion (very low certainty).

1 finding from 1 review

Rifapentine plus isoniazid weekly vs isoniazid

Treatment‐limiting adverse events · HIV‐negative people at risk of TB infection1

Rifapentine plus isoniazid weekly probably leads to higher treatment‐limiting adverse events compared with isoniazid daily (moderate certainty).

1 finding from 1 review