Cochrane · systematic review · CD006086

Nutritional supplements for people being treated for active tuberculosis

Grobler, L, Nagpal, S, Sudarsanam, TD, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Infectious Diseases2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 16.7%Very low 6 · 50%Low 3 · 25%Moderate 1 · 8.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

'Summary of findings' table 1

Population: adults and children with active tuberculosis
6 questions
OutcomeEffectEvidenceStatus / GRADE
Death (at 6 months)
RR 0.34 [0.1, 1.2]4 studies · 567 participantsVery low
Downgraded: imprecision, indirectness
Cured (at 6 months)
RR 0.91 [0.59, 1.41]1 study · 102 participantsVery low
Downgraded: imprecision, indirectness
Treatment completion (at 6 months)
no estimate extracted2 studies · 365 participantsVery low
Downgraded: imprecision, inconsistency
Sputum negative (at 8 weeks)
RR 1.08 [0.86, 1.37]3 studies · 222 participantsVery low
Downgraded: imprecision, inconsistency
Mean weight gain (At 8 weeks)
no estimate extracted5 studies · 883 participantsModerate
Downgraded: inconsistency
Quality of life (At 8 weeks)
no estimate extracted2 studies · 134 participantsLow
Downgraded: imprecision, indirectness

'Summary of findings' table 2

Population: adults and children with active tuberculosis
6 questions
OutcomeEffectEvidenceStatus / GRADE
Death
RR 0.86 [0.46, 1.6]4 studies · 1219 participantsLow
Downgraded: imprecision, inconsistency
Cure rate
no estimate extracted0 studies · 0 participantsUngraded
Treatment completion
RR 0.99 [0.95, 1.04]1 study · 302 participantsVery low
Downgraded: imprecision, indirectness
Remaining sputum positive (at 4 weeks)
RR 0.92 [0.63, 1.35]2 studies · 1020 participantsVery low
Downgraded: imprecision, inconsistency, indirectness
Weight gain
no estimate extracted5 studies · 2940 participantsLow
Downgraded: imprecision, inconsistency
Quality of life
no estimate extracted0 studies · 0 participantsUngraded