Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

11 questions · 11 findings · 4 reviews · Common Mental Disorders

No studies found 0 · 0%GRADE not reported 1 · 9.1%Very low 4 · 36.4%Low 6 · 54.5%Moderate 0 · 0%High 0 · 0%

Summary of findings: Specialist inpatient care for weight restoration vs active outpatient or combination brief hospital/outpatient care

Weight or BMI (at end of 12 months from the start of treatment) · participants with anorexia nervosa

Summary of findings: Specialist inpatient care for weight restoration showed no clear difference in weight or BMI (at end of 12 months from the start of treatment) compared with active outpatient or combination brief hospital/outpatient care (low certainty).

1 finding from 1 review

Summary of findings: Specialist inpatient care for weight restoration vs active outpatient or combination brief hospital/outpatient care

Secondary outcome: acceptability of treatment · participants with anorexia nervosa

It is very uncertain whether summary of findings: Specialist inpatient care for weight restoration changes acceptability: number of participants who completed treatment (at… compared with active outpatient or combination brief hospital/outpatient care (very low certainty).

1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs psychological interventions

Drug or alcohol use, or both following treatment completion ‐ Individual‐based intervention · Individuals with post‐traumatic stress disorder and comorbid substance use disorder
1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs psychological interventions

Treatment completers · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

It is very uncertain whether non‐trauma‐focused psychological intervention for PTSD and SUD or… changes treatment completers compared with active psychological intervention (very low certainty).

1 finding from 1 review

Trauma‐focused psychological intervention vs psychological interventions

Treatment completers · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

Trauma‐focused psychological intervention showed no clear difference in treatment completers compared with active psychological intervention (low certainty).

1 finding from 1 review

Lamotrigine vs lithium

Recurrence of any episodes at one year (active suicidal behavior) · bipolar disorder

It is very uncertain whether lamotrigine changes recurrence of any episodes at one year (active suicidal behavior) compared with lithium (very low certainty).

1 finding from 1 review