Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

85 questions · 85 findings · 10 reviews · Infectious Diseases · Headline outcomes only

No studies found 13 · 15.3%GRADE not reported 14 · 16.5%Very low 21 · 24.7%Low 18 · 21.2%Moderate 12 · 14.1%High 7 · 8.2%

MVA85A vs placebo

Active tuberculosis: confirmed by culture or Xpert® MTB/RIF longest reported · HIV‐positive and ‐negative adults and children

MVA85A showed no clear difference in active tuberculosis: confirmed by culture or Xpert® MTB/RIF longest… compared with placebo (moderate certainty).

1 finding from 1 review

MVA85A vs placebo

Active tuberculosis: started on tuberculosis treatment · HIV‐positive and ‐negative adults and children

MVA85A showed no clear difference in active tuberculosis: started on tuberculosis treatment compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Cure or completion of treatment for active TB · Recipients of TB control services

The intervention showed no clear difference in cure or completion of treatment for active TB (low certainty).

1 finding from 1 review

Intervention not reported

Death (at 6 months) · adults and children with active tuberculosis

It is very uncertain whether the intervention changes death (at 6 months) (very low certainty).

1 finding from 1 review

Intervention not reported

Remaining sputum positive (at 4 weeks) · adults and children with active tuberculosis

It is very uncertain whether the intervention changes remaining sputum positive (at 4 weeks) (very low certainty).

1 finding from 1 review