Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 4 reviews · Endodontics and dental trauma · All outcomes

No studies found 5 · 71.4%GRADE not reported 1 · 14.3%Very low 1 · 14.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Placebo (sham irradiation, laser inactive) vs Control (no laser device used)

Maximum pain (verbal rating scale, VRS) · People requiring retreatment of periapical lesions (failed root canal therapy)

Placebo (sham irradiation, laser inactive) led to lower maximum pain (verbal rating scale, VRS) compared with control (no laser device used); GRADE not reported.

1 finding from 1 review

Bio-active restorative materials vs Any conventional restorative material

Treatment failure (planned; no eligible studies) · Children with carious primary teeth after vital or non-vital pulp therapy

No eligible studies were found evaluating bio-active restorative materials for restoring carious primary teeth after pulp therapy.

1 finding from 1 review

Bio-active restorative materials vs Any restorative material or technique

Not applicable (no eligible studies) · Children with carious primary teeth (no pulp therapy)

No eligible RCTs assessed new bio-active restorative materials in carious primary teeth; this is an evidence gap identified by the review.

1 finding from 1 review

Ultrasonic instrumentation used alone (any ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal) vs Hand instrumentation used alone (files and reamers used manually)

Outcome not reported · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of internal resorption,…

The review found no eligible studies for this question.

1 finding from 1 review

Hand instrumentation in conjunction with (as an adjunct to) an ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal vs Hand instrumentation used alone (files and reamers used manually)

Outcome not reported · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of internal resorption,…

The review found no eligible studies for this question.

1 finding from 1 review