Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

150 questions · 169 findings · 22 reviews · All outcomes

No studies found 52 · 30.8%GRADE not reported 78 · 46.2%Very low 20 · 11.8%Low 13 · 7.7%Moderate 6 · 3.6%High 0 · 0%

ITI SLActive titanium grade 4 implants vs ITI SLActive titanium-13zirconium (Roxolid) implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

ITI SLActive titanium grade 4 implants showed no clear difference in implant failure compared with ITI SLActive titanium-13zirconium (Roxolid) implants; GRADE not reported.

1 finding from 1 review

NobelActive external connection implants vs NobelActive internal connection implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive external connection implants showed no clear difference in marginal bone level change compared with nobelActive internal connection implants; GRADE not reported.

1 finding from 1 review

NobelActive external connection implants vs NobelActive internal connection implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive external connection implants showed no clear difference in implant failure compared with nobelActive internal connection implants; GRADE not reported.

1 finding from 1 review

One active intervention (surgical, medical, or psychological) vs A different active intervention (direct head-to-head comparison)

Outcome not reported · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Active self-ligating brackets vs Passive self-ligating brackets

Time to alignment · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Active self-ligating brackets showed no clear difference in time to alignment (days) compared with passive self-ligating brackets; GRADE not reported.

1 finding from 1 review

Active self-ligating brackets vs Passive self-ligating brackets

Amount of crowding (upper anterior crowding) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
1 finding from 1 review
  • Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
    baseline
    Only baseline upper anterior crowding reported (Pandis 2010a, n=70); evidence of baseline imbalance between groups (P=0.04); no post-treatment between-group crowding estimate reported.
    1 study
    GRADE not reported

NobelActive external connection implants vs NobelReplace implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive external connection implants showed no clear difference in implant failure compared with nobelReplace implants; GRADE not reported.

1 finding from 1 review

NobelActive internal connection implants vs NobelReplace implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive internal connection implants showed no clear difference in marginal bone level change compared with nobelReplace implants; GRADE not reported.

1 finding from 1 review

NobelActive external connection implants vs NobelReplace implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive external connection implants showed no clear difference in marginal bone level change compared with nobelReplace implants; GRADE not reported.

1 finding from 1 review

NobelActive internal connection implants vs Nobel Speedy Groovy external connection implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive internal connection implants led to lower marginal bone level change compared with nobel Speedy Groovy external connection implants; GRADE not reported.

1 finding from 1 review

NobelActive internal connection implants vs NobelReplace implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive internal connection implants showed no clear difference in implant failure compared with nobelReplace implants; GRADE not reported.

1 finding from 1 review

Placebo (sham irradiation, laser inactive) vs Control (no laser device used)

Maximum pain (verbal rating scale, VRS) · People requiring retreatment of periapical lesions (failed root canal therapy)

Placebo (sham irradiation, laser inactive) led to lower maximum pain (verbal rating scale, VRS) compared with control (no laser device used); GRADE not reported.

1 finding from 1 review

Active rinse (zinc acetate + chlorhexidine + sodium fluoride), with or without tongue scraping vs Negative control rinse, with or without tongue scraping

OLT and VSC scores · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    Ademovski 2012 (4-arm cross-over trial) compared an active rinse (with/without tongue scraping) versus a negative control rinse (with/without tongue scraping); OLT and VSC. The authors did not report the correlation…
    1 study
    GRADE not reported

Ultrasonic instrumentation used alone (any ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal) vs Hand instrumentation used alone (files and reamers used manually)

Outcome not reported · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of internal resorption,…

The review found no eligible studies for this question.

1 finding from 1 review

Hand instrumentation in conjunction with (as an adjunct to) an ultrasonic device designed specifically for root canal treatment and capable of the active or passive removal of dentine within the root canal vs Hand instrumentation used alone (files and reamers used manually)

Outcome not reported · People over 18 years of age with single or multiple permanent teeth with a completely formed apex and no evidence of internal resorption,…

The review found no eligible studies for this question.

1 finding from 1 review

Periodontal treatment: scaling and root planing (SRP) plus advice vs Community care: advice only

Serum high-sensitivity C-reactive protein (hs-CRP) · Patients with cardiovascular disease and chronic periodontitis
1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Duration of orthodontic treatment, number of visits during active treatment (scheduled and unscheduled) and duration of visits · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Capitation remuneration vs Fee-for-service remuneration

Measures of clinical activity: mean percentage of 0- to 15-year-olds receiving active preventive advice · Children (0- to 15-year-olds) undergoing routine continuing dental care at 354 dental practices, in matched pairs of Health Service…

Capitation remuneration may leads to higher measures of clinical activity: mean percentage of 0- to 15-year-olds… compared with fee-for-service remuneration (low certainty).

4 findings from 1 review
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