Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

20 questions · 20 findings · 3 reviews · Pregnancy and Childbirth

No studies found 3 · 15%GRADE not reported 0 · 0%Very low 3 · 15%Low 1 · 5%Moderate 5 · 25%High 8 · 40%

Laxative plus bulking agent vs laxative alone

Adverse effects on women: faecal incontinence during first 10 postpartum days · postpartum women who underwent surgical repair of third degree perineal tears

It is very uncertain whether laxative plus bulking agent changes adverse effects on women: faecal incontinence during first 10… compared with laxative alone (very low certainty).

1 finding from 1 review

Standard care plus IV tranexamic acid vs placebo or usual care

Maternal mortality due to bleeding · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in maternal mortality due to bleeding compared with placebo or standard care alone (moderate certainty).

1 finding from 1 review

Standard care plus IV tranexamic acid vs placebo or usual care

Maternal mortality ‐ not reported · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in maternal mortality (all causes) compared with placebo or standard care alone (moderate certainty).

1 finding from 1 review

Standard care plus IV tranexamic acid vs placebo or usual care

Serious maternal morbidity · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in serious maternal morbidity (any) compared with placebo or standard care alone (high certainty).

1 finding from 1 review

Standard care plus IV tranexamic acid vs placebo or usual care

Maternal blood loss of 500 mL or greater · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid may leads to lower blood loss 500 mL or more after randomisation compared with placebo or standard care alone (low certainty).

1 finding from 1 review

Standard care plus IV tranexamic acid vs placebo or usual care

Blood transfusion · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in blood transfusion (any) compared with placebo or standard care alone (moderate certainty).

1 finding from 1 review

Standard care plus IV tranexamic acid vs placebo or usual care

Hysterectomy to control bleeding · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in surgical intervention to control bleeding: Hysterectomy compared with placebo or standard care alone (high certainty).

1 finding from 1 review

Standard care plus IV tranexamic acid vs placebo or usual care

Side effects of the intervention: Any maternal vascular occlusive event · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in side effects of the intervention: Any maternal vascular occlusive… compared with placebo or standard care alone (moderate certainty).

1 finding from 1 review

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography (CTG) vs CTG alone

Caesarean section ‐ ST analysis · Pregnant women (and their fetuses) in labour, with a perceived need for continuous electronic fetal heart rate monitoring

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography… showed no clear difference in caesarean section ‐ ST analysis compared with CTG alone (high certainty).

1 finding from 1 review

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography (CTG) vs CTG alone

Cord pH less than 7.05 and base deficit greater than 12 mmol/L ‐ ST analysis · Pregnant women (and their fetuses) in labour, with a perceived need for continuous electronic fetal heart rate monitoring

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography… showed no clear difference in cord pH less than 7.05 and base deficit greater than 12 mmol/L ‐ ST… compared with CTG alone (moderate certainty).

1 finding from 1 review

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography (CTG) vs CTG alone

Neonatal encephalopathy ‐ ST analysis · Pregnant women (and their fetuses) in labour, with a perceived need for continuous electronic fetal heart rate monitoring

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography… showed no clear difference in neonatal encephalopathy ‐ ST analysis compared with CTG alone (high certainty).

1 finding from 1 review

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography (CTG) vs CTG alone

Fetal blood sampling ‐ ST analysis · Pregnant women (and their fetuses) in labour, with a perceived need for continuous electronic fetal heart rate monitoring

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography… leads to lower fetal blood sampling ‐ ST analysis compared with CTG alone (high certainty).

1 finding from 1 review

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography (CTG) vs CTG alone

Instrumental vaginal birth · Pregnant women (and their fetuses) in labour, with a perceived need for continuous electronic fetal heart rate monitoring

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography… leads to lower operative vaginal delivery ‐ ST analysis compared with CTG alone (high certainty).

1 finding from 1 review

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography (CTG) vs CTG alone

Neonatal admission to special care · Pregnant women (and their fetuses) in labour, with a perceived need for continuous electronic fetal heart rate monitoring

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography… showed no clear difference in admission to neonatal special care unit ‐ ST analysis compared with CTG alone (high certainty).

1 finding from 1 review

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography (CTG) vs CTG alone

Any perinatal death after randomisation · Pregnant women (and their fetuses) in labour, with a perceived need for continuous electronic fetal heart rate monitoring

Fetal electrocardiogram (ECG) (ST analysis) plus cardiotocography… showed no clear difference in perinatal death ‐ ST analysis compared with CTG alone (high certainty).

1 finding from 1 review